Tanaka Yuko, Bhunchet Ekapot, Shibata Toshikatsu
Department of Surgery, Tsuchiura Kyodo General Hospital, 11-7 Manabeshin-machi, Tsuchiura, Ibaraki, 300-0053, Japan.
Breast Cancer. 2008;15(2):175-80. doi: 10.1007/s12282-007-0023-y. Epub 2008 Feb 13.
Eccrine spiradenoma (ES) is a fairly common, benign, cutaneous tumor originating from the sweat glands. In contrast, the malignant counterpart of ES, malignant eccrine spiradenoma (MES), is extremely rare. A long-standing lesion rarely begins to enlarge rapidly. A growth that results in ulceration or discoloration may be associated with malignant transformation. We present the first reported case of this tumor metastasizing to an intramammary lymph node (IMLN). The uncommon metastasizing focus of the periumbilical MES and its histopathological similarity with a primary breast carcinoma made the diagnosis difficult.
小汗腺螺旋腺瘤(ES)是一种相当常见的起源于汗腺的良性皮肤肿瘤。相比之下,ES的恶性对应物,恶性小汗腺螺旋腺瘤(MES)极为罕见。长期存在的病变很少会突然迅速增大。导致溃疡或变色的肿物可能与恶变有关。我们报告了首例该肿瘤转移至乳腺内淋巴结(IMLN)的病例。脐周MES这种不常见的转移灶及其与原发性乳腺癌的组织病理学相似性使得诊断颇具难度。