Carreira José M, Reyes Ricardo, Gude Francisco, Górriz Elías, Gallardo Laura, Pardo María Dolores, Hermida María
Universidad de Santiago de Compostela, Santiago de Compostela, Spain.
Minim Invasive Ther Allied Technol. 2008;17(1):34-42. doi: 10.1080/13645700701800343.
The purpose of this study was to evaluate the long-term results of iliac artery stent placement with use of the symphony stent for the treatment of patients with intermittent claudication. In a prospective study, 31 cases of iliac occlusive arterial disease were treated in 26 patients. Stenoses (n = 27) were treated after failed angioplasty, and occlusions (n = 4) were treated with primary stent placement. Clinical history, clinical stage and the ankle brachial-index (ABI) examination measurement were assessed. The patients were followed up with clinical examination, ABI examination measurement and intravenous angiography. The follow-up period ranged between 9.5 months and 7.5 years (median = 5.9 yr). Data were analyzed using the univariate analysis (Kaplan-Meier method). The mean+/-SD ABI pre-, post-procedure and in the last control was 0.70+/-0.17, 0.97+/-0.15, and 0.96+/-0.20, respectively. Primary patency rates (%) +/- SE were 83+/-7 after 3 years, 75+/-8 after five years, and 67+/-9 after seven years, and secondary patency rates were 93+/-5 after three years, 86+/-7 after five years, and 86+/-7 after seven years. During the first 24 hours, one patient presented occlusion of the treated segment. During follow-up, 9 (29%) patients were admitted to our hospital because of worsening of the symptoms. In this study, the symphony stent has been proven to be a good device to treat lesions in the iliac region but more experience is needed to optimize endovascular treatment in this area. In our experience the treatment of iliac artery occlusive disease with symphony stents can be considered a good option with acceptable patency rates and low morbidity and mortality.
本研究的目的是评估使用Symphony支架置入术治疗间歇性跛行患者的髂动脉长期疗效。在一项前瞻性研究中，26例患者接受了31例髂动脉闭塞性疾病的治疗。27例狭窄患者在血管成形术失败后接受治疗，4例闭塞患者接受初次支架置入术。评估患者的临床病史、临床分期及踝肱指数（ABI）检查测量值。通过临床检查、ABI检查测量值及静脉血管造影对患者进行随访。随访期为9.5个月至7.5年（中位数 = 5.9年）。采用单因素分析（Kaplan-Meier法）对数据进行分析。术前、术后及末次随访时的平均±标准差ABI分别为0.70±0.17、0.97±0.15和0.96±0.20。3年、5年和7年的一期通畅率（%）±标准误分别为83±7、75±8和67±9，二期通畅率分别为93±5、86±7和86±7。在最初24小时内，1例患者出现治疗节段闭塞。随访期间，9例（29%）患者因症状加重入院。在本研究中，Symphony支架已被证明是治疗髂动脉病变的良好器械，但需要更多经验来优化该区域的血管内治疗。根据我们的经验，使用Symphony支架治疗髂动脉闭塞性疾病可被视为一种具有可接受通畅率、低发病率和死亡率的良好选择。
