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Mineralocorticoid receptors in brain, in health and disease: possibilities for new pharmacotherapy.

作者信息

Kellner Michael, Wiedemann Klaus

机构信息

University Hospital Hamburg-Eppendorf, Department of Psychiatry and Psychotherapy, Martinistrasse 52, D-20246 Hamburg, Germany.

出版信息

Eur J Pharmacol. 2008 Apr 7;583(2-3):372-8. doi: 10.1016/j.ejphar.2007.07.072. Epub 2008 Jan 19.

Abstract

Mineralocorticoid receptors in brain are involved in the regulation of stress hormone secretion and complex behavior, such as emotion, memory, and sleep. In man, the role of mineralocorticoid receptors in the pathophysiology of stress-related psychiatric disorders has still not sufficiently been characterized. Nevertheless, recent research findings promise possibilities for new pharmacotherapy via modulation of mineralocorticoid receptor function.

摘要

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