Tachon Romain, Pichon Valérie, Barbe Le Borgne Martine, Minet Jean-Jacques
Laboratoire Central de la Préfecture de Police, 39 bis rue de Dantzig, Paris, France.
J Chromatogr A. 2008 Mar 21;1185(1):1-8. doi: 10.1016/j.chroma.2008.01.026. Epub 2008 Jan 17.
A solid-phase extraction procedure was developed for the clean-up of forensic samples collected at bombing scenes. Recoveries of common organic explosives from methanolic extracts diluted with water were studied on different hydrophobic sorbents. Polymeric sorbents retained explosive compounds better than octadecyl-bonded silica-based materials. Clean-up efficiency was evaluated with simulated samples prepared from commercial motor oil. Polymeric sorbent with the smallest specific surface area was found to limit the coextraction of matrix components. Performance of the method was confirmed by a reduction of ion suppression in LC/MS analysis.
开发了一种固相萃取方法，用于净化在爆炸现场收集的法医样本。研究了在不同疏水性吸附剂上，从用水稀释的甲醇提取物中回收常见有机炸药的情况。聚合物吸附剂比十八烷基键合硅胶基材料能更好地保留炸药化合物。用从商用机油制备的模拟样品评估了净化效率。发现比表面积最小的聚合物吸附剂能限制基质成分的共萃取。通过液相色谱/质谱分析中离子抑制的降低，证实了该方法的性能。
