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1
TLC1 RNA nucleo-cytoplasmic trafficking links telomerase biogenesis to its recruitment to telomeres.
EMBO J. 2008 Mar 5;27(5):748-57. doi: 10.1038/emboj.2008.21. Epub 2008 Feb 14.
2
The principal role of Ku in telomere length maintenance is promotion of Est1 association with telomeres.
Genetics. 2014 Aug;197(4):1123-36. doi: 10.1534/genetics.114.164707. Epub 2014 May 30.
3
Telomerase RNA TLC1 shuttling to the cytoplasm requires mRNA export factors and is important for telomere maintenance.
Cell Rep. 2014 Sep 25;8(6):1630-1638. doi: 10.1016/j.celrep.2014.08.021. Epub 2014 Sep 15.
4
Biogenesis of yeast telomerase depends on the importin mtr10.
Mol Cell Biol. 2002 Sep;22(17):6046-55. doi: 10.1128/MCB.22.17.6046-6055.2002.
5
Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres.
PLoS Genet. 2008 Oct;4(10):e1000236. doi: 10.1371/journal.pgen.1000236. Epub 2008 Oct 24.
8
The Est3 protein is a subunit of yeast telomerase.
Curr Biol. 2000 Jun 29;10(13):809-12. doi: 10.1016/s0960-9822(00)00562-5.
9
Rif2 protects Rap1-depleted telomeres from MRX-mediated degradation in .
Elife. 2022 Jan 19;11:e74090. doi: 10.7554/eLife.74090.
10
Stability and nuclear localization of yeast telomerase depend on protein components of RNase P/MRP.
Nat Commun. 2020 May 1;11(1):2173. doi: 10.1038/s41467-020-15875-9.

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2
Trafficking of the telomerase RNA using a novel genetic approach.
PLoS One. 2025 Apr 2;20(4):e0313178. doi: 10.1371/journal.pone.0313178. eCollection 2025.
4
TERC promotes non-small cell lung cancer progression by facilitating the nuclear localization of TERT.
iScience. 2024 May 3;27(6):109869. doi: 10.1016/j.isci.2024.109869. eCollection 2024 Jun 21.
5
DNA-PK participates in pre-rRNA biogenesis independent of DNA double-strand break repair.
Nucleic Acids Res. 2024 Jun 24;52(11):6360-6375. doi: 10.1093/nar/gkae316.
6
Advances in understanding telomerase assembly.
Biochem Soc Trans. 2023 Dec 20;51(6):2093-2101. doi: 10.1042/BST20230269.
7
Methods that shaped telomerase research.
Biogerontology. 2024 Apr;25(2):249-263. doi: 10.1007/s10522-023-10073-8. Epub 2023 Oct 31.
10
Telomerase subunit Est2 marks internal sites that are prone to accumulate DNA damage.
BMC Biol. 2021 Nov 20;19(1):247. doi: 10.1186/s12915-021-01167-1.

本文引用的文献

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Tel1p preferentially associates with short telomeres to stimulate their elongation.
Mol Cell. 2007 Sep 7;27(5):851-8. doi: 10.1016/j.molcel.2007.08.007.
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Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae.
Mol Cell. 2007 Aug 17;27(4):550-61. doi: 10.1016/j.molcel.2007.07.016. Epub 2007 Jul 26.
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Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs.
Nat Rev Mol Cell Biol. 2007 Mar;8(3):209-20. doi: 10.1038/nrm2124.
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S. cerevisiae Tel1p and Mre11p are required for normal levels of Est1p and Est2p telomere association.
Mol Cell. 2006 Nov 17;24(4):603-10. doi: 10.1016/j.molcel.2006.10.005.
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RNase III-dependent regulation of yeast telomerase.
J Biol Chem. 2007 Feb 16;282(7):4373-4381. doi: 10.1074/jbc.M607145200. Epub 2006 Dec 11.
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Low abundance of telomerase in yeast: implications for telomerase haploinsufficiency.
RNA. 2006 Sep;12(9):1721-37. doi: 10.1261/rna.134706. Epub 2006 Aug 7.
8
Telomere length homeostasis.
Chromosoma. 2006 Dec;115(6):413-25. doi: 10.1007/s00412-006-0067-3. Epub 2006 Jun 2.
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Cellular dynamics of small RNAs.
Crit Rev Biochem Mol Biol. 2006 Jan-Feb;41(1):3-19. doi: 10.1080/10409230500405237.
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Cell cycle-regulated trafficking of human telomerase to telomeres.
Mol Biol Cell. 2006 Feb;17(2):955-65. doi: 10.1091/mbc.e05-09-0903. Epub 2005 Dec 7.

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