裸金属支架内的极晚期血栓形成：一个未得到充分认识的问题。
Very late thrombosis in a bare metal stent: an under-recognized problem.
作者信息
Fineschi Massimo, Gori Tommaso
机构信息
UO Emodinamica, Azienda Universitaria Ospedaliera Senese, Siena, Italy.
出版信息
Can J Cardiol. 2008 Feb;24(2):e6-7. doi: 10.1016/s0828-282x(08)70575-0.
Abstract
Recent publications have emphasized the concept that restenosis of a bare metal stent is not as clinically benign as previously believed. A case of very late (seven years) thrombosis after implantation of a bare metal stent is described. While doubts on the long-term safety of drug-eluting stents are debated, registry data and clinical reports suggest that the long-term safety of coronary bare metal stent implantation should also be reconsidered.
摘要
近期的出版物强调了这样一个概念，即裸金属支架再狭窄在临床上并不像之前认为的那样无害。本文描述了一例裸金属支架植入术后非常晚期（七年）发生血栓形成的病例。在关于药物洗脱支架长期安全性的疑虑仍在讨论之时，登记数据和临床报告表明，冠状动脉裸金属支架植入术的长期安全性也应重新审视。
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本文引用的文献
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Late or very late stent thrombosis can also occur with bare metal stents.裸金属支架也可能发生晚期或极晚期支架血栓形成。
Catheter Cardiovasc Interv. 2007 Aug 1;70(2):229-32. doi: 10.1002/ccd.21077.
2
Recurrent very late stent thrombosis after bare-metal stent implantation.裸金属支架植入术后复发性极晚期支架内血栓形成。
Catheter Cardiovasc Interv. 2007 Jul 1;70(1):51-3. doi: 10.1002/ccd.21044.
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Late clinical events after clopidogrel discontinuation may limit the benefit of drug-eluting stents: an observational study of drug-eluting versus bare-metal stents.停用氯吡格雷后的晚期临床事件可能会限制药物洗脱支架的益处：一项药物洗脱支架与裸金属支架的观察性研究
J Am Coll Cardiol. 2006 Dec 19;48(12):2584-91. doi: 10.1016/j.jacc.2006.10.026. Epub 2006 Nov 2.
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Histopathological findings of new in-stent lesions developed beyond five years.五年后出现的新支架内病变的组织病理学发现。
Catheter Cardiovasc Interv. 2006 Oct;68(4):554-8. doi: 10.1002/ccd.20787.
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Effectiveness and safety of sirolimus stent implantation for coronary in-stent restenosis: the TRUE (Tuscany Registry of Sirolimus for Unselected In-Stent Restenosis) Registry.
J Am Coll Cardiol. 2006 Jul 18;48(2):270-5. doi: 10.1016/j.jacc.2006.03.039. Epub 2006 Jun 23.
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Bare metal stent restenosis is not a benign clinical entity.裸金属支架再狭窄并非一种良性临床情况。
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