Pătraşcu V, Georgescu Claudia Valentina, Tănase Loredana Elena, Mogoantă S S
Department of Dermatology, Emergency County Hospital of Craiova, University of Medicine and Pharmacy of Craiova, Craiova, Romania.
Rom J Morphol Embryol. 2008;49(1):91-6.
Lupus vulgaris (LV) is the most frequent cutaneous tuberculosis, representing more than 55% of the tuberculoses with this location. Malignization can occur after a long latency (10-30 years), in 1-2% of the cases, and it is mainly in squamous cell carcinoma. The histological exam is highly important in the observation of neoplasic transformations. The authors present a 59-years-old female patient, from the rural environment, working as a farmer, with lupus vulgaris developing since her first childhood years. It started at the age of 2 years, at the right ear lobule, after the empiric perforation for earrings. The evolution was progressive, eccentric, interesting the pinna and the right cheek in the meanwhile. At the first examination, in 2002, a diffuse mass of red-yellowish infiltration was found at the level of the right ear and the right cheek. In the following two years, an ulcero-vegetating tumor developed at the level of the right ear lobule, accompanied by the presence of a right retromandibular adenopathy, of about 1 cm, which was proved by the histopathologic exam to be a squamous cell carcinoma developed from a lupus vulgaris. After scraping out the right retromandibular ganglion, detected by palpation, a histological exam showed ganglion metastasis.
寻常狼疮（LV）是最常见的皮肤结核，占该部位结核病的55%以上。恶变可在长时间潜伏期（10 - 30年）后发生，发生率为1% - 2%，主要为鳞状细胞癌。组织学检查对观察肿瘤转化非常重要。作者介绍了一名59岁的女性患者，来自农村，职业为农民，自幼患有寻常狼疮。该病始于2岁时右耳垂，因穿耳洞经验性穿孔后发病。病情呈进行性、离心性发展，同时累及耳廓和右脸颊。2002年首次检查时，右耳和右脸颊处发现弥漫性红黄色浸润性肿块。在接下来的两年里，右耳垂处出现溃疡性增殖性肿瘤，伴有约1厘米大小的右下颌后腺病，组织病理学检查证实为寻常狼疮发展而来的鳞状细胞癌。刮除通过触诊检测到的右下颌后神经节后，组织学检查显示有神经节转移。
