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[麻风病:病例报告及文献综述]

[Hansen's disease: case report and review of literature].

作者信息

Concha R Marcela, Cossio T M Laura, Salazar S Iván, Fich S Félix, Pérez C Carlos, González B Sergio

机构信息

Departamento de Dermatología, Pontificia Universidad Católica de Chile, Santiago, Chile.

出版信息

Rev Chilena Infectol. 2008 Feb;25(1):64-9. Epub 2008 Feb 8.

Abstract

Leprosy is a granulomatous disease affecting the skin and peripheral nerves caused by Mycobacterium leprae. The range of clinical forms varying from tuberculoid to lepromatous leprosy results from variations in the cellular immune response to the mycobacterium. Despite available combined drug-therapy, it continues to be a significant public health problem, carrying a strong stigma. Although recently there has been no native cases in Chile, a few imported cases have been diagnosed. We present a 56-year-old man who had lived in Paraguay for 8 years, and presented with leprosy 6 years after returning to Chile. The biology of leprosy, clinical features of the disease, current diagnostic criteria and approaches to treatment are discussed.

摘要

麻风病是一种由麻风分枝杆菌引起的影响皮肤和周围神经的肉芽肿性疾病。从结核样型到瘤型麻风的临床形式范围是由对该分枝杆菌的细胞免疫反应差异导致的。尽管有可用的联合药物疗法,但它仍然是一个重大的公共卫生问题,带有强烈的污名。尽管最近智利没有本土病例,但已诊断出一些输入性病例。我们报告一名56岁男子,他在巴拉圭生活了8年,回到智利6年后出现麻风病。本文讨论了麻风病的生物学特性、疾病的临床特征、当前的诊断标准和治疗方法。

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