Wheeler M D, Styne D M
Department of Pediatrics, University of California, School of Medicine, Davis.
Endocrinol Metab Clin North Am. 1991 Mar;20(1):183-90.
Long-acting GnRH agonists are the treatment of choice for central precocious puberty. GnRH agonists are not effective in peripheral precocious puberty, but a number of other agents, including medroxyprogesterone acetate, ketoconazole, testolactone, and androgen antagonists, may be useful.
长效促性腺激素释放激素(GnRH)激动剂是中枢性性早熟的首选治疗方法。GnRH激动剂在外周性早熟中无效,但许多其他药物,包括醋酸甲羟孕酮、酮康唑、睾酮内酯和雄激素拮抗剂,可能会有帮助。