Gurvit H, Emre M, Tinaz S, Bilgic B, Hanagasi H, Sahin H, Gurol E, Kvaloy J T, Harmanci H
Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Faculty of Medicine, Istanbul University, Capa, Istanbul, Turkey.
Am J Alzheimers Dis Other Demen. 2008 Feb-Mar;23(1):67-76. doi: 10.1177/1533317507310570.
A cross-sectional, population-based, 2-stage prevalence study was conducted in a sample of 1019 community-dwelling persons over the age of 70 years living in Istanbul. In the first phase, participants were screened with the Mini-Mental State Examination for evidence of cognitive impairment. In the second phase, 79% of those who screened positive (n = 322) and 9% of screen-negatives (n = 63) underwent a standardized diagnostic workup. Diagnosis of dementia and Alzheimer's disease (AD) was made according to established criteria. Ninety-three cases of dementia were identified, 58 of whom were diagnosed with probable AD. Based on these numbers, the prevalence rates of probable AD and dementia were calculated to be 11.0% (95% CI, 7.0% to 15.0%) and 20.0% (95% CI, 14.0% to 26.0%), respectively, in this population. Prevalence rates of dementia and AD in Istanbul, Turkey, are comparable with those seen in the Western world.
在伊斯坦布尔，对1019名年龄在70岁以上的社区居民样本进行了一项基于人群的两阶段横断面患病率研究。在第一阶段，使用简易精神状态检查表对参与者进行筛查，以寻找认知障碍的证据。在第二阶段，筛查呈阳性者（n = 322）中的79%和筛查呈阴性者（n = 63）中的9%接受了标准化的诊断检查。根据既定标准对痴呆症和阿尔茨海默病（AD）进行诊断。共识别出93例痴呆症病例，其中58例被诊断为可能的AD。根据这些数字，该人群中可能的AD和痴呆症的患病率分别计算为11.0%（95%CI，7.0%至15.0%）和20.0%（95%CI，14.0%至26.0%）。土耳其伊斯坦布尔的痴呆症和AD患病率与西方世界的患病率相当。
