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及时诊断共病的广泛性发育障碍和双相情感障碍。

Timely diagnosis of comorbid pervasive developmental disorder and bipolar disorder.

作者信息

McDonnell M A, Hamrin V, Moffett J, Durso S

机构信息

STEP UP for Kids, Inc., South Shore Psychiatric Services, PC Marshfield, MA, USA.

出版信息

Minerva Pediatr. 2008 Feb;60(1):115-27.

Abstract

Little is known about the overlapping symptoms and comorbidity of pediatric bipolar disorder (BD) and pervasive developmental disorders (PDD) in youth. The aim of this study was to clearly differentiate the symptoms, understand the prevalence and patterns of comorbid presentations, as well as to provide a summary of evidence-based research findings to improve timely diagnosis and treatment for comorbid PDD and BD in children and adolescents, and to provide clinicians with evidence-based research findings of the similarity and differences in symptom presentation, the epidemiology, and diagnostic strategies used by experts in the fields of PDD and pediatric BD. The sources for this study were published review and research articles. According to the results obtained, it can be observed that studies evaluating the epidemiology, symptom presentation and diagnosis of comorbid BD and PDD are limited. However, research studies identified a clear overlap in symptoms between the two disorders and the existence of comorbid PDD and BD. Children with PDD and comorbid BD may be significantly impaired. More extensive research is needed to facilitate timely diagnosis and treatment to improve quality of life and outcomes in this population.

摘要

关于青少年期小儿双相情感障碍(BD)与广泛性发育障碍(PDD)的重叠症状及共病情况,目前所知甚少。本研究的目的是明确区分症状,了解共病表现的患病率及模式,以及提供基于证据的研究结果总结,以改善对儿童及青少年共病PDD和BD的及时诊断与治疗,并为临床医生提供关于PDD和小儿BD领域专家所使用的症状表现异同、流行病学及诊断策略的基于证据的研究结果。本研究的资料来源为已发表的综述及研究文章。根据所得结果可以观察到,评估共病BD和PDD的流行病学、症状表现及诊断的研究有限。然而,研究发现这两种疾病之间症状存在明显重叠,且存在PDD和BD共病情况。患有PDD且合并BD的儿童可能会受到显著损害。需要进行更广泛的研究以促进及时诊断和治疗,从而改善这一人群的生活质量和预后。

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