Castellano-González Maribel, Ginestre-Pérez Messaria, Perozo-Mena Armindo, Alaña Freddy, Fernández-Bravo Marisol, Rincón-Villalobos Gresleida
Departamento de Microbiología, Escuela de Bioanálisis, Facultad de Medicina, Universidad del Zulia-Centro de Referencia Bacteriológica, Servicio Autónomo Hospital Universitario de Maracaibo, Venezuela.
Invest Clin. 2007 Dec;48(4):419-29.
To compare vaginal colonization by genital micoplasmas in pregnant and non pregnant women and to determine the association between pregnancy and colonization by these microorganisms, samples of exocervix an endocervix from pregnant (n = 80) and non pregnant (n = 65) women, from two health centers of Maracaibo, Zulia State, Venezuela were processed. The Mycoplasma-Lyo kit (bioMérieux laboratories) was used for the culture and identification of genital micoplasmas. In pregnant women, prevalences of 10% for M. hominis and 26.25% for Ureaplasma spp. were found; 35.38% for M. hominis and 20% for Ureaplasma spp. in non-pregnant, were obtained. Among the pregnant, Ureaplasma spp. was the most frequently isolated micoplasma, in symptomatic and asymptomatic; while in the non pregnant group, M. hominis was more common among the symptomatic patients; only one case (1.54%) was an asymptomatic carrier of Ureaplasma spp. The highest positivity percentages were obtained in primigravidas (48.71%) and during the second gestational trimester (34.21%). No statistically significant differences were found between vaginal colonization by genital micoplasmas according to age, number of pregnancy and gestational trimester; but they were found between the presented symptomatology and vaginal colonization by genital micoplasmas. Genital micoplasmas were isolated from gravid women at approximately the same recovery rate as in non-pregnant women; being M. hominis the most frequently isolated in non-pregnant women and Ureaplasma spp. in the pregnant group.
为比较孕妇和非孕妇生殖道支原体的阴道定植情况,并确定妊娠与这些微生物定植之间的关联,对来自委内瑞拉苏利亚州马拉开波市两个健康中心的80名孕妇和65名非孕妇的宫颈外口和宫颈内口样本进行了处理。使用Mycoplasma-Lyo试剂盒(生物梅里埃实验室)进行生殖道支原体的培养和鉴定。在孕妇中,人型支原体的患病率为10%,解脲脲原体的患病率为26.25%;在非孕妇中,人型支原体的患病率为35.38%,解脲脲原体的患病率为20%。在孕妇中,无论有无症状,解脲脲原体都是最常分离出的支原体;而在非孕妇组中,人型支原体在有症状的患者中更为常见;只有1例(1.54%)是解脲脲原体的无症状携带者。初产妇(48.71%)和妊娠中期(34.21%)的阳性率最高。根据年龄、妊娠次数和妊娠 trimester,生殖道支原体的阴道定植情况之间未发现统计学上的显著差异;但在出现的症状与生殖道支原体的阴道定植之间发现了差异。从孕妇中分离出生殖道支原体的回收率与非孕妇大致相同;在非孕妇中最常分离出的是人型支原体,而在孕妇组中是解脲脲原体。