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[药物性全血细胞减少症恢复期出现的耐甲氧西林金黄色葡萄球菌所致脓性肌炎]

[Methicillin-resistant Staphylococcus aureus-induced pyomyositis that emerged during recovery from drug-induced pancytopenia].

作者信息

Kobayashi Shinichi, Kimura Fumihiko, Ogura Kazuto, Kobayashi Ayako, Torikai Hiroki, Ikeda Takashi, Sato Ken, Saionji Katsu, Ito Teruyo, Saito Daizo, Motoyoshi Kazuo

机构信息

Division of Hematology, Department of Internal Medicine, National Defense Medical College.

出版信息

Rinsho Ketsueki. 2008 Jan;49(1):55-8.

Abstract

Pyomyositis is a purulent infection of skeletal muscle characterized by fever, localized muscle pain and stiffness, swelling and tenderness. Hematological disorder is one of the predisposing conditions for the development of pyomyositis. A 54-year-old man developed methicillin-resistant Staphylococcus aureus pyomyositis during drug-induced pancytopenia. Debridement of the infection foci combined with antimicrobial agents proved effective even in the advanced stage of the disease. In patients with hematological disorders, pyomyositis should be considered when evaluating local myalgia and high fever because this disease can be very difficult to identify and can become rapidly progressive under a myelosuppressive condition.

摘要

脓性肌炎是一种骨骼肌的化脓性感染,其特征为发热、局部肌肉疼痛和僵硬、肿胀及压痛。血液系统疾病是脓性肌炎发生的易感因素之一。一名54岁男性在药物性全血细胞减少期间发生了耐甲氧西林金黄色葡萄球菌脓性肌炎。即使在疾病晚期,感染灶清创术联合抗菌药物治疗也被证明是有效的。对于血液系统疾病患者,在评估局部肌痛和高热时应考虑脓性肌炎,因为这种疾病可能很难识别,并且在骨髓抑制状态下可能迅速进展。

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