Biesbrock Aaron R, Bartizek Robert D, Gerlach Robert W, Terézhalmy Géza T
The Procter & Gamble Company, Health Care Research Center, Mason, OH, USA.
J Clin Dent. 2007;18(4):101-5.
The purpose of this study was to examine the effects of various product combinations involving brush, paste, rinse, and floss on the prevention of plaque regrowth and gingivitis.
In this randomized, parallel-group, examiner-blind, eight-week study, 179 subjects with gingivitis had a dental prophylaxis and were randomly assigned to one of six product combinations: 1) Colgate Wave manual toothbrush + Colgate Total dentifrice (0.3% triclosan/copolymer dentifrice); 2) Wave + Total + Listerine (essential oils rinse); 3) Oral-B CrossAction manual toothbrush + Crest Pro-Health dentifrice (0.454% stannous fluoride/sodium hexametaphosphate); 4) CrossAction + Pro-Health dentifrice + Crest Pro-Health Rinse (0.07% cetylpyridinium chloride rinse); 5) Oral-B ProfessionalCare Series 8000 power toothbrush + Pro-Health dentifrice; or 6) ProfessionalCare power brush + Pro-Health dentifrice + Oral-B Hummingbird power flosser. Subjects used their test products for the duration of the study. Whole mouth plaque, gingivitis, and product-related adverse events were assessed. Treatments were compared at a 0.05 level of significance.
One-hundred and seventy-four subjects completed the study and were included in the data analysis. At Week 8, the overnight adjusted whole mouth plaque scores were statistically significantly lower in all other groups relative to the Wave + Total group (p < or = 0.030). Plaque scores were also statistically significantly lower (approximately 20%) in both groups where a therapeutic rinse was added to a manual brush and therapeutic paste relative to scores for the brush plus paste without a rinse (p < or = 0.034). All groups showed a reduction in gingivitis at Week 4, and mean scores remained stable or increased slightly at Week 8. The power toothbrush groups were directionally better at preventing gingivitis than the manual groups at Weeks 4 and 8.
Reductions in overnight plaque were seen when therapeutic rinses were added to manual brush plus therapeutic dentifrice regimens above that observed with a manual brush and therapeutic dentifrice alone.
本研究旨在探讨涉及牙刷、牙膏、漱口水和牙线的各种产品组合对预防牙菌斑再生长和牙龈炎的效果。
在这项随机、平行组、检查者盲法的为期八周的研究中，179名患有牙龈炎的受试者接受了牙齿预防治疗，并被随机分配到六种产品组合中的一种：1）高露洁波浪手动牙刷+高露洁全效牙膏（含0.3%三氯生/共聚物牙膏）；2）波浪牙刷+全效牙膏+李施德林漱口水（含精油漱口水）；3）欧乐-B交叉动作手动牙刷+佳洁士健康专家牙膏（含0.454%氟化亚锡/六偏磷酸钠）；4）交叉动作牙刷+健康专家牙膏+佳洁士健康专家漱口水（含0.07%西吡氯铵漱口水）；5）欧乐-B专业护理系列8000电动牙刷+健康专家牙膏；或6）专业护理电动牙刷+健康专家牙膏+欧乐-B蜂鸟电动牙线。受试者在研究期间使用他们的测试产品。评估全口牙菌斑、牙龈炎和与产品相关的不良事件。在0.05的显著性水平上比较各治疗组。
174名受试者完成了研究并被纳入数据分析。在第8周时，相对于波浪牙刷+全效牙膏组，所有其他组的过夜调整后全口牙菌斑评分在统计学上显著更低（p≤0.030）。在手动牙刷和治疗性牙膏基础上添加治疗性漱口水的两组，其牙菌斑评分也在统计学上显著更低（约低20%），相对于未添加漱口水的牙刷加牙膏组（p≤0.034）。所有组在第4周时牙龈炎均有所减轻，且在第8周时平均评分保持稳定或略有增加。在第4周和第8周时，电动牙刷组在预防牙龈炎方面在趋势上优于手动牙刷组。
当在手动牙刷加治疗性牙膏的方案中添加治疗性漱口水时，过夜牙菌斑减少，且比单独使用手动牙刷和治疗性牙膏时观察到的效果更好。
Zotero 插件