Paraskevas S, Versteeg P A, Timmerman M F, Van der Velden U, Van der Weijden G A
Department of Periodontology, Academic Center for Dentistry Amsterdam (ACTA), 1006 EA Amsterdam, The Netherlands.
J Clin Periodontol. 2005 Jul;32(7):757-64. doi: 10.1111/j.1600-051X.2005.00750.x.
To examine the effect of amine fluoride/stannous fluoride (AmF/SnF(2))-containing dentifrice and mouth rinse on plaque formation and gingivitis as compared with habitual oral hygiene procedures with a regular sodium fluoride (NaF) dentifrice.
In total, 22 general practices participated in this research project. The participants (N=281) were randomly assigned into two groups: the test group received an AmF/SnF(2) dentifrice-mouth rinse combination and the control group received a NaF-containing dentifrice. The patients were requested to brush twice daily for approximately 2 min. The subjects of the test group had to rinse additionally in the evening for 30 s with 10 ml of the mouth rinse.
Both groups started with comparable scores of plaque, bleeding and staining. At 6 months, the plaque scores were 0.95 for the AmF/SnF(2) group and 0.99 for the NaF group (decrease of 16% and 10%, respectively). Bleeding scores, although significantly different from baseline, did not show differences between the two regimes. At the end of the experimental period, the overall staining was more pronounced in the AmF/SnF(2) group (41%) than the NaF group (26%). Both plaque reduction and increase in staining seemed to be correlated to the amount of mouth rinse used in the test group.
In instruction-resistant patients recruited from dental practices, the combined use of AmF/SnF(2) did not decrease gingivitis at a significant level in comparison with the regular regime of two times daily brushing with an NaF-containing dentifrice. However, the above-mentioned combination resulted in greater plaque reduction than that observed with the use of the conventional dentifrice. When used according to the manufacturer's instructions, this effect on plaque scores was more pronounced.
与使用常规含氟牙膏进行日常口腔卫生护理相比,研究含胺氟/氟化亚锡(AmF/SnF₂)的牙膏和漱口水对牙菌斑形成和牙龈炎的影响。
共有22家全科诊所参与了本研究项目。参与者(N = 281)被随机分为两组:试验组使用含AmF/SnF₂的牙膏 - 漱口水组合,对照组使用含氟牙膏。要求患者每天刷牙两次,每次约2分钟。试验组的受试者晚上还需用10毫升漱口水额外漱口30秒。
两组开始时牙菌斑、出血和染色评分相当。6个月时,AmF/SnF₂组的牙菌斑评分为0.95,含氟牙膏组为0.99(分别下降了16%和10%)。出血评分虽然与基线有显著差异,但两种方案之间没有差异。在实验期结束时,AmF/SnF₂组的总体染色(41%)比含氟牙膏组(26%)更明显。牙菌斑减少和染色增加似乎都与试验组使用的漱口水用量有关。
在从牙科诊所招募的难以遵医嘱的患者中,与每天使用含氟牙膏刷牙两次的常规方案相比,联合使用AmF/SnF₂并没有显著降低牙龈炎。然而,上述组合导致的牙菌斑减少比使用传统牙膏更明显。按照制造商的说明使用时,这种对牙菌斑评分的影响更显著。