Greenberg Caprice C, Bafford Andrea C, Golshan Mehra
Department of Surgery, Brigham & Women's Hospital & Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Expert Rev Anticancer Ther. 2008 Feb;8(2):195-8. doi: 10.1586/14737140.8.2.195.
The standard of care in the management of the axilla for a woman with breast cancer was traditionally a level I and II axillary lymph node dissection (ALND). Since the pivotal studies in the mid-1990s, sentinel lymph node biopsy (SLNB) in breast carcinoma has come to replace ALND in women with clinically negative axillas. With the increased use of SLNB in women who present with breast carcinoma, the role of completion ALND for a positive sentinel lymph node has been challenged. We review the literature available and discuss future directions in identifying a subgroup who may avoid an ALND.
传统上,对于患有乳腺癌的女性,腋窝管理的护理标准是进行I级和II级腋窝淋巴结清扫术(ALND)。自20世纪90年代中期的关键研究以来,乳腺癌前哨淋巴结活检(SLNB)已逐渐取代临床腋窝阴性女性的ALND。随着SLNB在乳腺癌女性患者中的使用增加,前哨淋巴结阳性时进行腋窝淋巴结清扫术的作用受到了挑战。我们回顾了现有文献,并讨论了确定可能避免进行ALND的亚组的未来方向。