Sánchez Elisabeth, Regidor Enrique, de la Fuente Luis, Luquero Francisco J, de Mateo Salvador
Servicio de Medicina Preventiva, Hospital Clínico San Carlos, Madrid, España.
Med Clin (Barc). 2008 Feb 9;130(4):133-5. doi: 10.1157/13115769.
AIDS-related mortality has been classically associated with lowest socioeconomic groups. In Spain, the highly active antiretroviral therapy (HAART) is delivered without cost; therefore this treatment it should have reduced the great social inequalities in AIDS-mortality seen before the HAART era. This study aims to assess the absolute and relative socioeconomic differences in AIDS-mortality in the Region of Madrid after the introduction of HAART.
Two twenty-months cohorts were created, in 1996 and 2001, which correspond to an early and late HAART-era respectively. Absolute and relative differences in the AIDS-mortality rates were calculated for both periods using generalized linear models.
Absolute differences between the lowest and highest education level AIDS-related deaths decreased around 70% in the 2001 cohort. Those with lowest education level achieved the highest reduction rate, hence relative differences descended as well.
HAART has had an essential role in decreasing social inequalities in AIDS-mortality.
艾滋病相关死亡率一直以来都与社会经济地位最低的群体密切相关。在西班牙，高效抗逆转录病毒疗法（HAART）是免费提供的；因此，这种治疗方法本应减少HAART时代之前在艾滋病死亡率方面存在的巨大社会不平等现象。本研究旨在评估在引入HAART之后，马德里地区艾滋病死亡率方面的绝对和相对社会经济差异。
分别在1996年和2001年创建了两个为期20个月的队列，分别对应HAART时代的早期和晚期。使用广义线性模型计算这两个时期艾滋病死亡率的绝对和相对差异。
在2001年的队列中，教育水平最低和最高人群的艾滋病相关死亡的绝对差异下降了约70%。教育水平最低的人群下降率最高，因此相对差异也有所下降。
HAART在减少艾滋病死亡率方面的社会不平等方面发挥了重要作用。
