Salles Frederico, Anchieta Marcos, Costa Bezerra Patrícia, Torres Maria Lúcia G M, Queiroz Elizabeth, Faber Jorge
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Mar;105(3):e41-7. doi: 10.1016/j.tripleo.2007.09.028.
Aglossia is a rare anomaly caused by failed embryogenesis of the lateral lingual swellings and tuberculum impar from the fourth to eighth gestational weeks. Most cases of aglossia and hypoglossia reported in the literature were associated with limb deformities, cleft palate, deafness, situs inversus, and several syndromes, such as Moebius, Pierre Robin, and Hanhart. This report describes the case of a 14-year-old girl with complete aglossia. As the tongue plays an important role in facial growth, this patient had dentofacial deformities that affected the mandible in particular. She also had severe malocclusion and agenesis of permanent mandibular incisors. Thyroid dysfunction, recently associated with aglossia, was not observed. The use of rapid prototyping models of the jaws as an aid to osteogenic distraction of the mandibular symphysis is also described.
先天性无舌是一种罕见的异常情况，由妊娠第4至8周侧舌隆突和奇结节胚胎发育失败所致。文献报道的大多数先天性无舌和舌下发育不全病例与肢体畸形、腭裂、耳聋、脏器反位以及多种综合征有关，如莫比乌斯综合征、皮埃尔·罗宾综合征和汉哈特综合征。本报告描述了一名患有完全性先天性无舌的14岁女孩的病例。由于舌头在面部生长中起重要作用，该患者存在牙颌面畸形，尤其影响下颌骨。她还患有严重的错牙合畸形和恒牙下颌切牙先天缺失。未观察到近期与先天性无舌相关的甲状腺功能障碍。还描述了使用颌骨快速原型模型辅助下颌骨联合处成骨牵引的情况。
