Peters Madelon L, Schmidt Anton J M
Department of Medical Psychology, University of Limburg, 6200 MD MaastrichtThe Netherlands.
Pain. 1991 Jan;44(1):57-60. doi: 10.1016/0304-3959(91)90147-P.
Differences in pain sensitivity between chronic pain patients and healthy controls have been reported. Seltzer and Seltzer extended this line of research in studying the sensitivity to non-painful stimuli. They reported that the 2-point discrimination threshold of chronic pain patients was higher than that of control subjects. However, the study of Seltzer and Seltzer suffered from several methodological shortcomings. Therefore, in the present study we tried to replicate the findings in a group of chronic low back pain patients using a design that was believed to be methodologically stronger. Replication failed: no evidence was found for the hypothesis that chronic pain patients are less sensitive to non-painful stimuli. Further studies on various defined types of acute and chronic pain patients are required.
已有报道称慢性疼痛患者与健康对照者在疼痛敏感性上存在差异。塞尔策和塞尔策在研究对非疼痛性刺激的敏感性时扩展了这一研究方向。他们报告称，慢性疼痛患者的两点辨别阈值高于对照组受试者。然而，塞尔策和塞尔策的研究存在若干方法学上的缺陷。因此，在本研究中，我们试图采用一种被认为方法学上更强的设计，在一组慢性下背痛患者中复制这些发现。复制失败：未找到证据支持慢性疼痛患者对非疼痛性刺激敏感性较低这一假设。需要对各种明确类型的急慢性疼痛患者进行进一步研究。
