[Essential arterial hypertension and Leriche-Fontaine stage II obliterating vascular disease of the lower limbs. A new pharmacological approach with ketanserin].

The efficacy of ketanserin treatment (40 mg daily for 90 days) was evaluated in 88 patients with arterial hypertension combined with Leriche-Fontaine stage II obliterating arterial disease of the lower limbs. Already after one month's treatment satisfactory control of blood pressure was achieved and maintained during the following months. In parallel with pressure control, an obvious improvement of functional and instrumental parameters of arterial disease was observed (walking distance, Winsor index). The drug was well tolerated, so that treatment had never to be withdrawn.