关节内注射阿达木单抗治疗骨坏死和单关节类风湿关节炎。
Osteonecrosis and monoarticular rheumatoid arthritis treated with intra-articular adalimumab.
作者信息
Kobak Senol
机构信息
Department of Rheumatology, Manisa Hospital, Manisa, Turkey.
出版信息
Mod Rheumatol. 2008;18(3):290-2. doi: 10.1007/s10165-008-0040-5. Epub 2008 Feb 20.
PMID:18286352
Abstract
We report a 54-year-old patient with RA presented with osteonecrosis (ON) and monoarthritis of left knee remitting in the last 2 years. Monoarthritis was resistant to disease-modifying antirheumatic drugs (DMARDs) and intra-articular corticosteroids. Intra-articular administration of adalimumab provided a good clinical and radiographic response. Synovitis resolved and osteonecrosis disappeared almost totally.
摘要
我们报告了一名54岁的类风湿关节炎（RA）患者，其出现了骨坏死（ON），左膝单关节炎在过去2年中缓解。单关节炎对改善病情抗风湿药（DMARDs）和关节内注射皮质类固醇均耐药。关节内注射阿达木单抗带来了良好的临床和影像学反应。滑膜炎消退，骨坏死几乎完全消失。
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