Geller J D, Topper S F, Hashimoto K
Department of Dermatology and Syphilology, Wayne State University School of Medicine, Detroit, MI.
J Am Acad Dermatol. 1991 May;24(5 Pt 2):816-8. doi: 10.1016/0190-9622(91)70121-h.
Diffuse neonatal hemangiomatosis is a rare, frequently fatal disease characterized by multiple cutaneous and visceral hemangiomas. The skin, liver, lungs, intestines, and central nervous system are the most commonly affected organs. Death can result from high-output cardiac failure as a result of arteriovenous shunting. In this report we present a new constellation of findings in a patient with diffuse neonatal hemangiomatosis, namely, an absent corpus callosum, ectopia cordis (sternal agenesis) with median abdominal raphe, and tricuspid atresia.
弥漫性新生儿血管瘤病是一种罕见的、常致命的疾病，其特征为多发性皮肤和内脏血管瘤。皮肤、肝脏、肺、肠道和中枢神经系统是最常受累的器官。动静脉分流导致的高输出量心力衰竭可导致死亡。在本报告中，我们展示了一名弥漫性新生儿血管瘤病患者的一组新发现，即胼胝体缺失、心脏异位（胸骨发育不全）伴腹部正中缝和三尖瓣闭锁。
