Bosworth Hayden B, Powers Benjamin, Grubber Janet M, Thorpe Carolyn T, Olsen Maren K, Orr Melinda, Oddone Eugene Z
Center for Health Services Research in Primary Care, Durham Veterans Affairs Medical Center (152), Durham, NC, USA.
J Gen Intern Med. 2008 May;23(5):692-8. doi: 10.1007/s11606-008-0547-7. Epub 2008 Feb 21.
The objective of the study was to identify potential explanatory factors for racial differences in blood pressure (BP) control.
The design of the study was a cross-sectional study
PATIENTS/PARTICIPANTS: The study included 608 patients with hypertension who were either African American (50%) or white (50%) and who received primary care in Durham, NC.
Baseline data were obtained from the Take Control of Your Blood pressure study and included clinical, demographic, and psychosocial variables potentially related to clinic BP measures. African Americans were more likely than whites to have inadequate baseline clinic BP control as defined as greater than or equal to 140/90 mmHg (49% versus 34%; unadjusted odds ratio [OR] 1.8; 95% confidence interval [CI] 1.3-2.5). Among factors that may explain this disparity, being older, reporting hypertension medication nonadherence, reporting a hypertension diagnosis for more than 5 years, reporting high levels of stress, being worried about hypertension, and reporting an increased number of medication side effects were related to inadequate BP control. In adjusted analyses, African Americans continue to have poor BP control relative to whites; the magnitude of the association was reduced (OR = 1.5; 95% CI 1.0-2.1). Medication nonadherence, worries about hypertension, and older age (>70) continued to be related to poor BP control.
In this sample of hypertensive patients, there were a number of factors associated with poor BP control that partially explained the observed racial disparity in hypertension control including age, medication nonadherence, and worry about BP. Medication nonadherence is of particular interest because it is a potentially modifiable factor that might be used to reduce the racial disparity in BP control.
本研究的目的是确定血压(BP)控制方面种族差异的潜在解释因素。
本研究的设计为横断面研究。
患者/参与者:该研究纳入了608名高血压患者,他们要么是非裔美国人(50%),要么是白人(50%),且在北卡罗来纳州达勒姆接受初级保健。
基线数据来自“掌控你的血压”研究,包括可能与诊所血压测量相关的临床、人口统计学和心理社会变量。按照血压大于或等于140/90 mmHg的定义,非裔美国人比白人更有可能基线诊所血压控制不佳(49% 对34%;未调整优势比[OR] 1.8;95%置信区间[CI] 1.3 - 2.5)。在可能解释这种差异的因素中,年龄较大、报告高血压药物治疗依从性差、报告高血压诊断超过5年、报告压力水平高、担心高血压以及报告药物副作用数量增加与血压控制不佳有关。在调整分析中,相对于白人,非裔美国人的血压控制仍然较差;关联强度有所降低(OR = 1.5;95% CI 1.0 - 2.1)。药物治疗依从性差、担心高血压以及年龄较大(>70岁)仍然与血压控制不佳有关。
在这个高血压患者样本中,有许多与血压控制不佳相关的因素,这些因素部分解释了观察到的高血压控制方面的种族差异,包括年龄、药物治疗依从性差和对血压的担忧。药物治疗依从性差特别值得关注,因为它是一个潜在可改变的因素,可能用于减少血压控制方面的种族差异。