Gianfrani Carmen, Troncone Riccardo, La Cava Antonio
Institute of Food Sciences of CNR, Avellino, Italy.
Mini Rev Med Chem. 2008 Feb;8(2):129-34. doi: 10.2174/138955708783498113.
In celiac disease (CD), abnormal immune-mediated responses follow ingestion of gluten. Although the triggering agent is a dietary protein, the disease has autoimmune components because of the presence of autoantibodies and its association with autoimmune conditions. We review the most recent studies on CD pathogenesis and the possibilities to modulate immune dysfunction in CD.
在乳糜泻(CD)中,摄入麸质后会引发异常的免疫介导反应。尽管触发因素是一种饮食蛋白,但由于自身抗体的存在及其与自身免疫性疾病的关联,该疾病具有自身免疫成分。我们综述了关于乳糜泻发病机制的最新研究以及调节乳糜泻免疫功能障碍的可能性。