Lesèche G, Batellier J, Bouttier S, Andreassian B
Service du Pr Andreassian, Hôpital Beaujon, Clichy.
Presse Med. 1991 Jun 1;20(21):992-6.
Despite improvements in the treatment of risk factors for atherosclerosis, the incidence and mortality rate for aneurysms of the abdominal aorta have increased during the past 40 years. The prevalence of these aneurysms is 2.5 percent in unselected populations but reaches 13.5 percent in selected populations. The pathogenesis of aneurysms involves multiple factors and the lesion is progressive, leading to lethal rupture in 25 percent of the cases. In elective surgery of abdominal aortic aneurysms the mortality rate is about 2 percent, as against 60 percent in emergency surgery for rupture. The presence of such aneurysms must be detected primarily in populations at risk, using physical examination and abdominal ultrasonography. If this is done, the ratio of detection costs to benefits of preventive surgery is in favour of a decidedly active approach of this dangerous disease.
尽管在动脉粥样硬化危险因素的治疗方面有所改善，但在过去40年中，腹主动脉瘤的发病率和死亡率仍有所上升。这些动脉瘤在未经过筛选的人群中的患病率为2.5%，但在经过筛选的人群中则达到13.5%。动脉瘤的发病机制涉及多个因素，且病变呈进行性发展，25%的病例会导致致命性破裂。在腹主动脉瘤择期手术中，死亡率约为2%，而破裂后急诊手术的死亡率则为60%。必须主要通过体格检查和腹部超声检查，在高危人群中检测出此类动脉瘤的存在。如果做到这一点，检测成本与预防性手术效益的比率有利于对这种危险疾病采取积极主动的治疗方法。
