Zuberbühler B, Grob M, Haefliger E
Augenklinik, Vista Klinik, Binningen, Schweiz.
Klin Monbl Augenheilkd. 2008 Feb;225(2):146-50. doi: 10.1055/s-2008-1027178.
The aim of this study was to evaluate the predictability and visual outcome of a foldable silicone iris-fixated phakic intraocular lens (Artiflex, Ophtec) for the correction of moderate to high myopia.
A retrospective cohort study with 34 eyes of 20 patients was undertaken. All patients underwent similar lens implantation with iris enclavation. The follow-up was 6 months.
At the final visit, 81% of eyes were within 0.5 D of the target spherical equivalent. Intraocular lenses with -12.0 to -14.5 D power showed a mean overcorrection of +0.81 D. The highest mean overcorrection of +1.45 D was shown by the Artiflex lenses with -14.5 D of power. The postoperative refraction remained stable, but the postoperative uncorrected and best-corrected visual acuity increased over time. 56% of eyes gained 1 or more Snellen lines of best-corrected visual acuity; one eye lost one line. No intraoperative complication was noticed. Two eyes showed prolonged intraocular inflammation.
The implantation of the phakic Artiflex intraocular lens was safe and showed a good predictability and safety for the correction of moderate to high myopia. It is an efficient alternative for laser in-situ keratomileusis, especially in high myopia, leading to a stable refraction one month postoperatively.
本研究旨在评估可折叠硅酮虹膜固定型有晶状体眼人工晶状体（Artiflex，Ophtec）矫正中度至高度近视的可预测性和视觉效果。
对20例患者的34只眼进行回顾性队列研究。所有患者均接受了类似的虹膜夹固定晶状体植入手术。随访时间为6个月。
在最后一次随访时，81%的眼的等效球镜度数在目标度数±0.5 D范围内。-12.0至-14.5 D屈光度的人工晶状体平均过矫+0.81 D。屈光度为-14.5 D的Artiflex人工晶状体平均过矫最高，为+1.45 D。术后屈光状态保持稳定，但术后未矫正视力和最佳矫正视力随时间提高。56%的眼最佳矫正视力提高了1行或更多行；1只眼下降了1行。未观察到术中并发症。2只眼出现了持续性眼内炎症。
植入有晶状体眼Artiflex人工晶状体矫正中度至高度近视安全，可预测性和安全性良好。对于准分子原位角膜磨镶术来说，它是一种有效的替代方法，尤其适用于高度近视，术后1个月屈光稳定。
