Ylöstalo P, Cacciatore B, Koskimies A, Kääriäinen M, Lehtovirta P, Mäkelä P, Siegberg R, Stenman U H, Tenhunen A, Ylikorkala O
Department of Obstetrics and Gynecology, University of Helsinki, Finland.
Ann N Y Acad Sci. 1991;626:516-23. doi: 10.1111/j.1749-6632.1991.tb37943.x.
As a conservative nonsurgical treatment of an early ectopic pregnancy, local prostaglandin, parenteral or local methotrexate, local hyperosmolar glucose, and also expectant management have been used successfully in selected cases. The success rate of conservative treatment has been 71%-100% and that of tubal patency after different kinds of conservative treatment 72-93% of patients. In the present study of expectant management in early ectopic pregnancy in patients with decreasing serum hCG levels, spontaneous resolution was observed in 64.6% of patients and in the total series of 207 ectopic pregnancies in 15.0% of patients. Expectant management of early ectopic pregnancy is recommended when emergency surgery is not needed on admission and the serum hCG level is decreasing as noted in two consecutive estimations with an interval of 1-2 days.
作为早期异位妊娠的保守非手术治疗方法，局部使用前列腺素、胃肠外或局部使用甲氨蝶呤、局部使用高渗葡萄糖，以及期待疗法在特定病例中均已成功应用。保守治疗的成功率为71% - 100%，不同类型保守治疗后输卵管通畅率为72% - 93%的患者。在本项针对血清hCG水平下降的早期异位妊娠患者进行期待疗法的研究中，64.6%的患者出现自然消退，在207例异位妊娠的总病例系列中，15.0%的患者出现自然消退。当入院时不需要急诊手术且血清hCG水平如在间隔1 - 2天的连续两次测定中所显示的那样下降时，建议对早期异位妊娠进行期待疗法。
