Rodríguez-Domínguez F J, Hernández-Gil J, Segarra Fenoll J D, Hernández-Gil A
Hospital Santa María del Rosell, Cartagena, Murcia.
An Otorrinolaringol Ibero Am. 2007;34(6):549-55.
Basosquamous carcinoma is a rare epithelial malignant neoplasm with clinical and biological features of both basal and squamous cell carcinoma. This neoplasm has been characterized for years as a variant of basal cell carcinoma, although now it is widely accepted as a clinical entity. We report a 59-year-old male patient, homeless, who presented an ulcerated tumoral lesion from four years ago, located in left malar region, orbit and nasal pyramid. It caused an important destruction of these anatomic structures and spred out the skull base through optic nerve. The most important features of basosquamous carcinoma are its great local aggressiveness, high frequency of recurrences and its metastatic potential. Because of that, the most effective therapeutic measure is the early detection and complete removement of these tumours; although, as the case we report, it is not always possible.
基底鳞状细胞癌是一种罕见的上皮性恶性肿瘤,具有基底细胞癌和鳞状细胞癌的临床及生物学特征。多年来,这种肿瘤一直被视为基底细胞癌的一种变体,尽管现在它已被广泛认可为一种临床实体。我们报告一例59岁男性患者,无家可归,四年前左颧部、眼眶和鼻锥体出现溃疡性肿瘤病变。它对这些解剖结构造成了严重破坏,并通过视神经蔓延至颅底。基底鳞状细胞癌最重要的特征是其极强的局部侵袭性、高复发率和转移潜能。因此,最有效的治疗措施是早期发现并彻底切除这些肿瘤;然而,如我们所报告的病例所示,这并非总是可行的。