《实施》集群随机对照试验伴随的经济评价方案。
Protocol for economic evaluation alongside the IMPLEMENT cluster randomised controlled trial.
机构信息
Centre for Health Economics, Faculty of Business & Economics, Monash University, Melbourne, Australia.
出版信息
Implement Sci. 2008 Feb 22;3:12. doi: 10.1186/1748-5908-3-12.
Abstract
BACKGROUND
The recent development and publication of evidence-based clinical practice guidelines (CPGs) for acute low back pain (LBP) has resulted in evidence-based recommendations that, if implemented, have the potential to improve the quality and safety of care for acute LBP. While a strategy has been specified for dissemination of the CPG for acute LBP in Australia, there is no accompanying plan for active implementation. Evidence regarding the cost-effectiveness of active implementation of CPGs for acute LBP is sparse. The IMPLEMENT study will consider the incremental benefits and costs of progressing beyond development and dissemination to implementation.
METHODS/DESIGN: Cost-effectiveness and cost-utility analyses alongside the IMPLEMENT cluster randomised controlled trial (CRCT) from a societal perspective to quantify the additional costs (savings) and health gains associated with a targeted implementation strategy as compared with access to the CPG via dissemination only.
DISCUSSION
The protocol provided here registers our intent to conduct an economic evaluation alongside the IMPLEMENT study, facilitates peer-review of proposed methods and provides a transparent statement of planned analyses.
摘要
背景
近期，针对急性腰痛（LBP）的循证临床实践指南（CPGs）的制定和发布，提出了循证推荐意见。如果这些推荐意见得到实施，将有可能改善急性 LBP 的医疗质量和安全性。虽然已经为急性 LBP 的 CPG 在澳大利亚的传播制定了策略，但没有配套的积极实施计划。关于积极实施急性 LBP 的 CPG 的成本效益的证据很少。IMPLEMENT 研究将考虑超出开发和传播阶段到实施阶段的增量收益和成本。
方法/设计：从社会角度出发，通过成本效益和成本效用分析以及 IMPLEMENT 群组随机对照试验（CRCT），定量评估与仅通过传播获得 CPG 相比，采用有针对性的实施策略所带来的额外成本（节省）和健康收益。
讨论
本方案注册了我们打算在 IMPLEMENT 研究中进行经济评估的意向，便于同行评审拟议方法，并提供计划分析的透明说明。
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