Pearce Anna, Elliman David, Bedford Helen, Law Catherine
Centre for Paediatric Epidemiology and Biostatistics, UCL Institute of Child Health, London, UK.
Vaccine. 2008 Mar 20;26(13):1675-80. doi: 10.1016/j.vaccine.2008.01.031. Epub 2008 Feb 4.
It has been hypothesised that lower vaccine uptake in childhood among some groups, such as children of lone parents or from larger families, may be due to their higher levels of residential mobility. This paper aimed to explore this association in a large cohort of children born in the UK at the turn of the century. Using multi-variable Poisson regression we found that children who lived in families which had moved during pregnancy or more frequently were more likely to be partially immunised with the primary immunisations and unimmunised against measles, mumps and rubella. Mobility was not associated with being unimmunised with the primary vaccines, or with single measles, mumps and rubella antigen vaccine use. These findings suggest that policies are needed to encourage the building and maintenance of relationships between health care professionals and parents, before and after they move, and better use of IT systems to aid follow-up of mobile families.
有假设认为，某些群体（如单亲家庭的孩子或来自大家庭的孩子）在儿童时期疫苗接种率较低，可能是因为他们的居住流动性较高。本文旨在对世纪之交在英国出生的一大群儿童进行研究，以探究这种关联。通过多变量泊松回归分析，我们发现，在孕期搬家或搬家更频繁的家庭中成长的孩子，更有可能未完成基础免疫接种，且未接种麻疹、腮腺炎和风疹疫苗。流动性与未接种基础疫苗或单独接种麻疹、腮腺炎和风疹抗原疫苗并无关联。这些研究结果表明，需要制定相关政策，鼓励医护人员在家庭搬家前后与家长建立并维持联系，并更好地利用信息技术系统，以协助对流动家庭进行跟进。
