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营养在优化峰值骨量方面的作用。

The role of nutrition on optimizing peak bone mass.

作者信息

Weaver Connie M

机构信息

Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907-2059, USA.

出版信息

Asia Pac J Clin Nutr. 2008;17 Suppl 1:135-7.

Abstract

The growth years provide an important window of opportunity for building peak bone mass. More than one-fourth of adult bone mass is acquired between the ages of 12 to 14 years in girls and 13 to 15 years in boys. Although genetics determine 60-80% of peak bone mass, lifestyle choices including diet and physical activity are also predictors of bone accrual during growth. Calcium and vitamin D are two nutrients that are most likely to be deficient. Dietary calcium predicts 10-15% of skeletal calcium retention during adolescence with race and sexual maturity in the models. Boys retain more calcium than girls and black girls retain more calcium than whites girls. The role of Vitamin D status on peak bone mass is not well understood. Results of randomized, controlled trials are mixed and the effects of vitamin D supplementation on calcium absorption in children has not been studied. Dietary salt increases urinary calcium excretion. Exercise can enhance the effect of dietary calcium through enhanced bone geometry.

摘要

生长阶段为建立峰值骨量提供了一个重要的机会窗口。超过四分之一的成人骨量是在女孩12至14岁、男孩13至15岁期间获得的。尽管基因决定了60 - 80%的峰值骨量,但包括饮食和体育活动在内的生活方式选择也是生长期间骨量积累的预测因素。钙和维生素D是最有可能缺乏的两种营养素。在模型中,饮食钙可预测青春期骨骼钙保留量的10 - 15%,同时还受种族和性成熟度影响。男孩比女孩保留更多的钙,黑人女孩比白人女孩保留更多的钙。维生素D状态对峰值骨量的作用尚不清楚。随机对照试验的结果不一,且尚未研究维生素D补充剂对儿童钙吸收的影响。饮食中的盐会增加尿钙排泄。运动可以通过改善骨骼结构来增强饮食钙的效果。

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