Petrie Ashley, Trak-Fellermeier Maria Angélica, Hernandez Jacqueline, Macchi Alison, Martinez-Motta Preciosa, Galván Rodolfo, Hernandez Yolangel, Martinez Rebeca, Palacios Cristina
Department of Dietetics and Nutrition, Robert Stempel College of Public Health & Social Work, Florida International University, 11200 SW 8th Street AHC5, Miami, FL, 33199, USA.
Department of Obstetrics and Gynecology, Herbert Wertheim College of Medicine, Florida International University, 11200 SW 8th Street, AHC2, Miami, FL, 33199, USA.
Arch Osteoporos. 2025 Jan 28;20(1):16. doi: 10.1007/s11657-025-01497-5.
Dietary acid load could be associated with bone mass, but there are limited and conflicting results. This secondary cross-sectional analysis evaluated these associations among 123 children/adolescents, mostly Hispanics. Dietary acid load seems to be associated with bone mass in boys, but these results should be confirmed through long-term studies.
Childhood/adolescence is key for developing strong bones. With the continuing rise in osteoporosis rates in Western societies, attention has turned to the possible impact of diets that create high levels of acid in the body. Some studies have shown an association between dietary acid load and bone mass, but there are limited studies in children/adolescents and none in Hispanics.
This study aimed to evaluate the associations between dietary acid load (assessed as dietary potential renal acid load, PRAL, and protein to potassium ratio) and whole-body bone mineral content (BMC) and density (BMD) in a sample of 123 children and adolescents of predominantly Hispanic ethnicity.
This study is a secondary cross-sectional analysis.
Dietary PRAL was positively associated with BMC and BMD overall (p < 0.05) and with BMC in boys (p < 0.05) when adjusted for energy misreporting only. The vegetable protein to potassium ratio was inversely associated with BMC (p = 0.004) in boys only, after adjusting for important factors.
Dietary acid load seems to be associated with BMC in boys in this sample of primarily Hispanic children. Long-term studies are needed to confirm these results and to understand the importance of protein intake in relation to other key nutrients in bone mass acquisition among Hispanic boys.
饮食酸负荷可能与骨量有关，但相关结果有限且相互矛盾。这项二次横断面分析评估了123名儿童/青少年（大多为西班牙裔）中的这些关联。饮食酸负荷似乎与男孩的骨量有关，但这些结果应通过长期研究来证实。
儿童期/青少年期是骨骼强壮发育的关键时期。随着西方社会骨质疏松症发病率的持续上升，人们开始关注在体内产生高酸度的饮食可能带来的影响。一些研究表明饮食酸负荷与骨量之间存在关联，但针对儿童/青少年的研究有限，且尚无针对西班牙裔的研究。
本研究旨在评估123名主要为西班牙裔的儿童和青少年样本中，饮食酸负荷（以饮食潜在肾酸负荷PRAL和蛋白质与钾的比值评估）与全身骨矿物质含量（BMC）和骨密度（BMD）之间的关联。
本研究为二次横断面分析。
仅在调整能量误报后，饮食PRAL总体上与BMC和BMD呈正相关（p < 0.05），与男孩的BMC呈正相关（p < 0.05）。在调整重要因素后，仅在男孩中，植物蛋白与钾的比值与BMC呈负相关（p = 0.004）。
在这个主要为西班牙裔儿童的样本中，饮食酸负荷似乎与男孩的BMC有关。需要进行长期研究来证实这些结果，并了解蛋白质摄入量与西班牙裔男孩骨量获取中其他关键营养素之间的关系的重要性。
