Anderson Kirstie N, Jamieson Sarah, Graham Andrew J, Shneerson John M
Respiratory Support and Sleep Centre, Papworth Hospital, Papworth Everard, Cambridge CB3 8RE, United Kingdom.
Clin Neurol Neurosurg. 2008 May;110(5):492-5. doi: 10.1016/j.clineuro.2008.01.004. Epub 2008 Mar 4.
We report a case of a 68-year-old man with probable Alzheimer's disease who developed rapid eye movement (REM) sleep behaviour disorder. This was confirmed with polysomnography but the patient also had some sleep apnea, which prevented the use of clonazepam for treatment. Melatonin was successfully used as an alternative treatment.
我们报告了一例68岁可能患有阿尔茨海默病的男性患者，他出现了快速眼动（REM）睡眠行为障碍。这通过多导睡眠图得到了证实，但该患者同时还存在一些睡眠呼吸暂停，这使得无法使用氯硝西泮进行治疗。褪黑素作为替代治疗被成功应用。
