Adamson T A, Fasoranti B, Adamson I
Neuropsychiatric Hospital, Abeokuta, Nigeria.
West Afr J Med. 1991 Jan-Mar;10(1):420-5.
Serum tryptophan and erythrocyte Na+/K+ ATPase were determined in 14 epileptics with and without psychosis. The nature of the psychosis in four patients was non-specific. The amino acid and the enzyme levels were also estimated in 11 patients with a diagnosis of functional affective psychosis, 14 patients with schizophrenia, and 9 normal subjects. Comparison of data among the patients and the normal subjects were done using analysis of variance. There were no significant differences in tryptophan profiles and Na+/K+ ATPase levels in epileptics with or without psychosis. In addition, the data obtained for these parameters for the schizophrenics were homogenous to those of epileptics. Significant differences were, however, obtained between the epileptics and patients with affective illness. The data thus suggested that the non-specific psychosis presented by the epileptics may be schizophrenia-like and lend support to a specific psychosis associated with epilepsy.
对14名有或无精神病的癫痫患者测定了血清色氨酸和红细胞钠钾ATP酶。4名患者的精神病性质不具有特异性。还对11名诊断为功能性情感性精神病的患者、14名精神分裂症患者和9名正常受试者的氨基酸和酶水平进行了评估。使用方差分析对患者和正常受试者的数据进行比较。有或无精神病的癫痫患者的色氨酸谱和钠钾ATP酶水平没有显著差异。此外，精神分裂症患者这些参数的数据与癫痫患者的数据相似。然而，癫痫患者与情感性疾病患者之间存在显著差异。因此，数据表明癫痫患者出现的非特异性精神病可能类似精神分裂症，并支持与癫痫相关的特定精神病。
