Lonberg-Holm K, Gosser L B, Shimshick E J
J Virol. 1976 Aug;19(2):746-9. doi: 10.1128/JVI.19.2.746-749.1976.
Subviral particles ("A particles") were produced from rhinovirus type 2 by treatment with acid and from poliovirus type 2 by incubation at 37 degrees C in a low-ionic-strength buffer. A particles, but not virions, adsorbed to liposomes. It is proposed that these reactions may provide an in vitro model for two early steps of infection.
通过酸处理从2型鼻病毒产生亚病毒颗粒(“A颗粒”),并通过在37℃下于低离子强度缓冲液中孵育从2型脊髓灰质炎病毒产生A颗粒。A颗粒而非病毒粒子吸附到脂质体上。有人提出,这些反应可能为感染的两个早期步骤提供一个体外模型。