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一匹野马渐进性虹膜黑素细胞瘤的外科治疗

Surgical management of a progressive iris melanocytoma in a Mustang.

作者信息

Scotty Nicole C, Barrie Kathleen B, Brooks Dennis E, Taylor David

机构信息

University of Minnesota Veterinary Medical Center, 1365 Gortner Ave., Saint Paul, MN 55108, USA.

出版信息

Vet Ophthalmol. 2008 Mar-Apr;11(2):75-80. doi: 10.1111/j.1463-5224.2008.00603.x.

Abstract

CASE DESCRIPTION

A 7-year-old gray Mustang gelding weighing 454 kg was presented for evaluation of a brown mass within the left eye (OS) of 1 year's duration with recent enlargement.

CLINICAL FINDINGS

A nonpainful, 8 mm diameter, brown, vascularized mass was identified in the anterior chamber of the OS. Ocular B-scan ultrasound confirmed iris involvement and corneal endothelial contact. Histopathology confirmed the presumptive diagnosis of a uveal melanocytic neoplasm, and revealed 1-3 mitotic figures per high power (400x) field.

TREATMENT AND OUTCOME

The mass was removed via sector iridectomy without complications, but without complete margins. Three cutaneous melanocytomas noted 1.5 months postoperatively were completely excised. No tumor regrowth was noted 15 months postoperatively, supporting a diagnosis of melanocytoma for the iridal mass.

CLINICAL RELEVANCE

Sector iridectomy is a reasonable treatment option for uncomplicated iridal melanocytomas in horses. Mitotic index and presence of cutaneous melanocytic neoplasms may be irrelevant to the prognosis of equine iridal melanocytic neoplasms.

摘要

病例描述

一匹7岁的灰色野马 gelding,体重454公斤,因左眼(OS)内一个持续1年且近期增大的褐色肿块前来评估。

临床检查结果

在左眼的前房发现一个无痛的、直径8毫米的褐色、血管化肿块。眼部B超检查证实虹膜受累且与角膜内皮接触。组织病理学证实了葡萄膜黑素细胞瘤的初步诊断,并显示每高倍视野(400倍)有1 - 3个有丝分裂象。

治疗及结果

通过扇形虹膜切除术切除肿块,无并发症,但切缘不完全。术后1.5个月发现的3个皮肤黑素细胞瘤被完全切除。术后15个月未发现肿瘤复发,支持虹膜肿块为黑素细胞瘤的诊断。

临床意义

扇形虹膜切除术是治疗马单纯性虹膜黑素细胞瘤的合理选择。有丝分裂指数和皮肤黑素细胞瘤的存在可能与马虹膜黑素细胞瘤的预后无关。

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