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马炎性角膜病的角膜移植:206例病例(1993 - 2007年)的视觉结果

Corneal transplantation for inflammatory keratopathies in the horse: visual outcome in 206 cases (1993-2007).

作者信息

Brooks D E, Plummer C E, Kallberg M E, Barrie K P, Ollivier F J, Hendrix D V H, Baker A, Scotty N C, Utter M E, Blackwood S E, Nunnery C M, Ben-Shlomo G, Gelatt K N

机构信息

Department of Large Animal Clinical Sciences, University of Florida, Gainesville, FL, USA.

出版信息

Vet Ophthalmol. 2008 Mar-Apr;11(2):123-33. doi: 10.1111/j.1463-5224.2008.00611.x.

Abstract

OBJECTIVE

To evaluate the visual outcome of three techniques of corneal transplantation surgery in treating severe inflammatory keratopathies in the horse.

DESIGN

Retrospective medical records study.

ANIMALS STUDIED

Medical records of 206 horses that received corneal transplantation surgery at the University of Florida Veterinary Medical Center from 1993 to 2007 were reviewed.

PROCEDURE

Data collected from the medical records included signalment, types of ocular lesions, type of transplant surgery performed, length of follow-up, complications, and visual outcomes.

RESULTS

Full thickness penetrating keratoplasty (PK) was performed in 86 horses for melting ulcers, iris prolapse/descemetoceles, and medically nonresponsive full thickness stromal abscesses (SA). Posterior lamellar keratoplasty (PLK) and deep lamellar endothelial keratoplasty (DLEK) are split thickness penetrating keratoplasties that were utilized for medically nonresponsive deep stromal abscesses (DSA) in 54 and 66 eyes, respectively. The most common postoperative surgical complication was graft rejection and varying degrees of graft opacification. Wound dehiscence and aqueous humor leakage was also a common postoperative problem. A positive visual outcome was achieved for PK, PLK, and DLEK in 77.9%, 98.1%, and 89.4%, respectively.

CONCLUSIONS

Corneal transplantation is a tectonically viable surgery in the horse with an overall success rate of 88.5% in maintaining vision when treating vascularized and infected corneal disease in the horse.

摘要

目的

评估三种角膜移植手术技术治疗马重度炎性角膜病的视觉效果。

设计

回顾性病历研究。

研究动物

对1993年至2007年在佛罗里达大学兽医学院接受角膜移植手术的206匹马的病历进行回顾。

程序

从病历中收集的数据包括特征、眼部病变类型、所施行的移植手术类型、随访时间、并发症和视觉效果。

结果

86匹马因溃疡穿孔、虹膜脱出/后弹力层膨出以及药物治疗无效的全层基质脓肿接受了全层穿透性角膜移植术(PK)。后板层角膜移植术(PLK)和深板层内皮角膜移植术(DLEK)均为分层穿透性角膜移植术,分别用于54只眼和66只眼中药物治疗无效的深层基质脓肿(DSA)。最常见的术后手术并发症是移植排斥反应和不同程度的移植片混浊。伤口裂开和房水渗漏也是常见的术后问题。PK、PLK和DLEK的视觉效果良好率分别为77.9%、98.1%和89.4%。

结论

角膜移植是马的一种可行的结构性手术,在治疗马的血管化和感染性角膜疾病时,维持视力的总体成功率为88.5%。

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