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后板层角膜移植术——同一患者深板层内皮角膜移植术与Descemet膜剥除自动内皮角膜移植术的比较:患者视角

Posterior lamellar keratoplasty--comparison of deep lamellar endothelial keratoplasty and Descemet stripping automated endothelial keratoplasty in the same patients: a patient's perspective.

作者信息

Bahar I, Sansanayudh W, Levinger E, Kaiserman I, Srinivasan S, Rootman D

机构信息

Department of Ophthalmology, Toronto Western Hospital, University of Toronto, 399 Bathurst Street, Toronto, Ontario, Canada.

出版信息

Br J Ophthalmol. 2009 Feb;93(2):186-90. doi: 10.1136/bjo.2007.136630. Epub 2008 Nov 19.

DOI:10.1136/bjo.2007.136630
PMID:19019944
Abstract

AIM

To evaluate patients' perspectives on endothelial keratoplasty and to compare the outcomes of deep lamellar endothelial keratoplasty (DLEK) and Descemet stripping automated endothelial keratoplasty (DSAEK), performed in the same patients.

METHODS

A fellow eye, comparative retrospective case series. The records of 14 patients (28 eyes) who underwent DLEK in one eye and DSAEK surgery in their fellow eye between 2003 and 2007 were reviewed. Two patients were excluded from the study. Both these techniques were compared for intra- and postoperative complications, visual and refractive outcomes including higher-order ocular aberrations (HOA). Patient satisfaction for both procedures was prospectively evaluated using a subjective questionnaire.

RESULTS

Nine (75%) of the 12 patients perceived better vision in the DSAEK operated eye. Eight (66.6%) of the patients reported faster recovery following DSAEK. Ten (83%) of them preferred the outcomes of the DSAEK surgery. The intra- and postoperative complications were comparable between both procedures. There was no significant difference in visual outcomes between the procedures. However, the DLEK procedure was associated with a significantly higher degree (p<0.05) of HOA. Endothelial cell loss was similar following DLEK and DSAEK.

CONCLUSIONS

We conclude that most patients prefer the DSAEK operation, although there are no differences in visual outcomes between DLEK and DSAEK. Avoidance of surgery-induced hyperopia and HOA is the main benefit of the DSAEK technique.

摘要

目的

评估患者对内皮角膜移植术的看法,并比较在同一患者中进行的深板层内皮角膜移植术(DLEK)和后弹力层剥除自动内皮角膜移植术(DSAEK)的效果。

方法

对侧眼、比较性回顾性病例系列研究。回顾了2003年至2007年间14例患者(28只眼)的记录,这些患者一只眼接受了DLEK手术,另一只眼接受了DSAEK手术。两名患者被排除在研究之外。比较了这两种技术的术中及术后并发症、视力和屈光结果,包括高阶像差(HOA)。使用主观问卷对两种手术的患者满意度进行了前瞻性评估。

结果

12例患者中有9例(75%)感觉DSAEK手术眼的视力更好。8例(66.6%)患者报告DSAEK术后恢复更快。其中10例(83%)更喜欢DSAEK手术的结果。两种手术的术中及术后并发症相当。两种手术的视力结果无显著差异。然而,DLEK手术与显著更高程度(p<0.05)的HOA相关。DLEK和DSAEK术后的内皮细胞丢失情况相似。

结论

我们得出结论,尽管DLEK和DSAEK的视力结果没有差异,但大多数患者更喜欢DSAEK手术。避免手术引起的远视和HOA是DSAEK技术的主要优势。

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