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一项失眠干预措施对乳腺癌幸存者疲劳、情绪及生活质量的疗效

Efficacy of an insomnia intervention on fatigue, mood and quality of life in breast cancer survivors.

作者信息

Dirksen Shannon R, Epstein Dana R

机构信息

College of Nursing and Healthcare Innovation, Arizona State University, Phoenix, Arizona, USA.

出版信息

J Adv Nurs. 2008 Mar;61(6):664-75. doi: 10.1111/j.1365-2648.2007.04560.x.

Abstract

AIM

This paper is a report of a study to describe the efficacy of cognitive behavioural therapy for insomnia on fatigue, mood and quality of life in breast cancer survivors.

BACKGROUND

Women who receive primary treatment for breast cancer often complain of insomnia. Rarely evaluated in insomnia intervention studies is the effect of cognitive behavioural treatment on the psychosocial outcomes of fatigue, mood and quality of life.

METHOD

Data were collected between December 2002 and March 2004 with 72 women who were at least 3 months post-completion of primary treatment without current evidence of disease. Women were randomly assigned to either the cognitive behavioural therapy for insomnia group, which received stimulus control instructions, sleep restriction therapy and sleep education and hygiene, or the component control group which received sleep education and hygiene only. The 10-week study consisted of 2 weeks of pre-treatment, 6 weeks of treatment and 2 weeks of post-treatment. Fatigue, mood and quality of life were measured at pre- and post-treatment.

FINDINGS

Women receiving cognitive behavioural therapy for insomnia had significant improvements in fatigue, trait anxiety, depression and quality of life. The component control group also had statistically significant increases in quality of life, with a trend suggestive of lower depression at post-treatment.

CONCLUSION

Globally, as the number of survivors in this population continues to grow, it is imperative that nurses continue testing interventions that may positively affect quality of life and the commonly experienced symptoms of fatigue, anxiety and depression.

摘要

目的

本文报告一项关于描述失眠认知行为疗法对乳腺癌幸存者疲劳、情绪及生活质量疗效的研究。

背景

接受乳腺癌初级治疗的女性常抱怨失眠。失眠干预研究中很少评估认知行为治疗对疲劳、情绪及生活质量等社会心理结果的影响。

方法

于2002年12月至2004年3月收集72名女性的数据,这些女性在完成初级治疗至少3个月后且目前无疾病证据。女性被随机分配至失眠认知行为治疗组,该组接受刺激控制指导、睡眠限制疗法以及睡眠教育与卫生指导,或仅接受睡眠教育与卫生指导的成分对照组。为期10周的研究包括2周的治疗前阶段、6周的治疗阶段以及2周的治疗后阶段。在治疗前和治疗后测量疲劳、情绪及生活质量。

结果

接受失眠认知行为疗法的女性在疲劳、特质焦虑、抑郁及生活质量方面有显著改善。成分对照组在生活质量方面也有统计学上的显著提高,治疗后有抑郁程度降低的趋势。

结论

总体而言,随着该人群中幸存者数量持续增加,护士必须继续测试可能对生活质量以及常见的疲劳、焦虑和抑郁症状产生积极影响的干预措施。

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