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针对乳腺癌幸存者失眠问题的认知行为干预随机试验。

Randomized trial of a cognitive-behavioral intervention for insomnia in breast cancer survivors.

作者信息

Epstein Dana R, Dirksen Shannon R

机构信息

Carl T. Hayden Veterans Affairs Medical Center and Clinics in Phoenix, AZ, USA.

出版信息

Oncol Nurs Forum. 2007 Sep;34(5):E51-9. doi: 10.1188/07.ONF.E51-E59.

DOI:10.1188/07.ONF.E51-E59
PMID:17878117
Abstract

PURPOSE/OBJECTIVES: To determine the efficacy of a cognitive-behavioral intervention for treating insomnia in breast cancer survivors.

DESIGN

Randomized controlled trial.

SETTING

University and medical center settings.

SAMPLE

72 women at least three months after primary treatment for breast cancer with sleep-onset or sleep maintenance insomnia at least three nights per week for at least three months as determined through daily sleep diaries.

METHODS

Random assignment to a multicomponent intervention (stimulus control instructions, sleep restriction, and sleep education and hygiene) or a single-component control group (sleep education and hygiene).

MAIN RESEARCH VARIABLES

Sleep-onset latency, wake after sleep onset, total sleep time, time in bed, sleep efficiency, and sleep quality.

FINDINGS

After the intervention, both groups improved on sleep-onset latency, wake after sleep onset, total sleep time, time in bed, sleep efficiency, and sleep quality based on daily sleep diaries. A between-group difference existed for time in bed. Wrist actigraph data showed significant pre- to postintervention changes for sleep-onset latency, wake after sleep onset, total sleep time, and time in bed. When compared to the control group, the multicomponent intervention group rated overall sleep as more improved.

CONCLUSIONS

A nonpharmacologic intervention is effective in the treatment of insomnia in breast cancer survivors.

IMPLICATIONS FOR NURSING

Breast cancer survivors can benefit from a cognitive-behavioral intervention for chronic insomnia. Sleep education and hygiene, a less complex treatment than a multicomponent intervention, also is effective in treating insomnia.

摘要

目的/目标:确定认知行为干预对治疗乳腺癌幸存者失眠症的疗效。

设计

随机对照试验。

地点

大学和医疗中心。

样本

72名女性,她们在乳腺癌初次治疗后至少三个月,根据每日睡眠日记确定每周至少三个晚上存在入睡或睡眠维持性失眠,且持续至少三个月。

方法

随机分配至多成分干预组(刺激控制指导、睡眠限制以及睡眠教育与卫生)或单成分对照组(睡眠教育与卫生)。

主要研究变量

入睡潜伏期、睡眠中觉醒时间、总睡眠时间、卧床时间、睡眠效率和睡眠质量。

研究结果

干预后,根据每日睡眠日记,两组在入睡潜伏期、睡眠中觉醒时间、总睡眠时间、卧床时间、睡眠效率和睡眠质量方面均有改善。两组在卧床时间上存在组间差异。腕部活动记录仪数据显示,干预前后入睡潜伏期、睡眠中觉醒时间、总睡眠时间和卧床时间有显著变化。与对照组相比,多成分干预组对整体睡眠改善的评价更高。

结论

非药物干预对治疗乳腺癌幸存者的失眠症有效。

对护理的启示

乳腺癌幸存者可从慢性失眠的认知行为干预中受益。睡眠教育与卫生作为一种比多成分干预更简单的治疗方法,对治疗失眠症也有效。

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