Saller Devereux N, Canick Jacob A
Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Virginia, Charlottesville, VA 22908, USA.
Clin Obstet Gynecol. 2008 Mar;51(1):24-36. doi: 10.1097/GRF.0b013e318160f274.
Prenatal diagnosis of Down syndrome is widely available, but the determination of which patients should undergo prenatal diagnosis is changing. With the recent acceptance of first-trimester and integrated screening as a part of routine clinical practice, there are now a variety of accepted screening protocols for Down syndrome and other aneuploidies. These choices can be confusing both to both patients and providers. The following discussion is meant to outline the various options in prenatal screening, and their individual advantages and disadvantages.
唐氏综合征的产前诊断已广泛开展，但关于哪些患者应接受产前诊断的判定标准正在发生变化。随着早孕期筛查和综合筛查最近被纳入常规临床实践，目前有多种被认可的唐氏综合征及其他非整倍体的筛查方案。这些选择可能会让患者和医疗服务提供者都感到困惑。以下讨论旨在概述产前筛查的各种选项及其各自的优缺点。
