Li Jianhong, Yang Lichen, Piao Jianhua, Yang Xiaoguang
Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Wei Sheng Yan Jiu. 2007 Nov;36(6):716-8.
To compare soluble transferring receptor (sTfR) levels between iron deficiency anemia and normal iron status in Chinese child-bearing women and study the critical value of sTfR assessing iron deficiency anemia.
251 normal iron status and 224 iron deficiency anemia of child-bearing women were drawn from National Nutrition and Health Survey (2002) as control group and case group respectively. The sTfR levels of two groups were determinated by enzyme linked immunosorbent assay (ELISA) and the critical value of sTfR assessing iron deficiency anemia was ascertained by ROC curve.
The levels of sTfR were (42.67 +/- 20.29) nmol/L and(21.08 +/- 6.70) nmol/L in case group and control group respectively and the former was higher than the latter significantly (P < 0.01). The optimal critical value of sTfR assessing iron deficiency anemia could be 25nmol/L.
The sTfR levels were more higher in iron deficiency anemia group of child-bearing women than those in normal iron status of child-bearing women. The critical value of sTfR assessing iron deficiency anemia may be more than 25nmol/L.
比较中国育龄妇女缺铁性贫血与铁状态正常者的可溶性转铁蛋白受体（sTfR）水平，并研究sTfR评估缺铁性贫血的临界值。
分别从2002年全国营养与健康调查中抽取251名铁状态正常的育龄妇女和224名缺铁性贫血的育龄妇女作为对照组和病例组。采用酶联免疫吸附测定法（ELISA）测定两组的sTfR水平，并通过ROC曲线确定sTfR评估缺铁性贫血的临界值。
病例组和对照组的sTfR水平分别为（42.67±20.29）nmol/L和（21.08±6.70）nmol/L，前者显著高于后者（P<0.01）。sTfR评估缺铁性贫血的最佳临界值可为25nmol/L。
育龄妇女缺铁性贫血组的sTfR水平高于育龄妇女铁状态正常组。sTfR评估缺铁性贫血的临界值可能大于25nmol/L。
