Lin Xianchai, Yu Minbin, Lü Lin, Fang Min, Li Jingrong
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
Yan Ke Xue Bao. 2007 Dec;23(4):238-42.
To evaluate the efficacy of combined trabeculectomy, lensectomy and vitrectomy for the management of secondary glaucoma in uveitis with extremely shallow anterior chamber and cataract.
Combined trabeculectomy, lensectomy and vitrectomy were undertaken for medically uncontrolled intraocular pressure (IOP) on 7 eyes (6 patients, aged from 4 months to 20 years) with secondary glaucoma in uveitis in a retrospective cohort study between 2001 and 2005.
The follow-up period ranged from 3 months to 4 years. Deep anterior chamber and functional bleb were observed in all the eyes postoperatively. The average IOP preoperatively, one day postoperatively, one week postoperatively, and the last time of follow-up were (5.18 +/- 0.77) kPa, (0.95 +/- 0.29) kPa, (0.93 +/- 0.12) kPa, and (1.14 +/- 0.70) kPa respectively. No severe complication was observed postoperatively except for the corneal edema and fiber exudation.
Combined trabeculectomy, lensectomy and vitrectomy serve as effective and safety treatments for secondary glaucomas uveitis accompanied by extremely shallow anterior chamber, cataract and vitreous opacity. Further intriguing study comparing this combined surgery with combined phacoemulsification and drainage implant surgery is warranted.
评估小梁切除术、晶状体切除术和玻璃体切除术联合治疗伴有极浅前房和白内障的葡萄膜炎继发性青光眼的疗效。
在2001年至2005年的一项回顾性队列研究中,对7只眼(6例患者,年龄4个月至20岁)伴有葡萄膜炎继发性青光眼且药物治疗无法控制眼压的患者进行小梁切除术、晶状体切除术和玻璃体切除术联合治疗。
随访时间为3个月至4年。术后所有眼均观察到前房加深且形成功能性滤过泡。术前、术后1天、术后1周及最后一次随访时的平均眼压分别为(5.18±0.77)kPa、(0.95±0.29)kPa、(0.93±0.12)kPa和(1.14±0.70)kPa。术后除角膜水肿和纤维渗出外,未观察到严重并发症。
小梁切除术、晶状体切除术和玻璃体切除术联合治疗是伴有极浅前房、白内障和玻璃体混浊的葡萄膜炎继发性青光眼的有效且安全的治疗方法。有必要进行进一步有趣的研究,将这种联合手术与超声乳化和引流植入联合手术进行比较。