Harrison Brooke A, Heck Shannon I, Hood Antoinette F
Eastern Virginia Medical School, Norfolk, USA.
Cutis. 2008 Jan;81(1):26-8.
Dermatomyositis (DM) is known to be associated with underlying malignancy, though the strength of this relationship and its predisposing factors are not clearly defined. We present a case of a patient who was first diagnosed with DM and, subsequently, metastatic esophageal adenocarcinoma. Despite aggressive immunosuppressive therapy, the patient's cutaneous eruption failed to resolve and his muscle weakness progressed. He had respiratory failure and died less than 2 months after his initial presentation. To our knowledge, this is only the second case of metastatic esophageal adenocarcinoma associated with DM reported in the English language literature.
皮肌炎(DM)已知与潜在恶性肿瘤相关,尽管这种关系的强度及其诱发因素尚未明确界定。我们报告一例患者,该患者最初被诊断为皮肌炎,随后被诊断为转移性食管腺癌。尽管进行了积极的免疫抑制治疗,但患者的皮肤皮疹未消退,肌肉无力进展。他出现呼吸衰竭,在首次就诊后不到2个月死亡。据我们所知,这是英文文献中报道的第二例与皮肌炎相关的转移性食管腺癌病例。