Jurcic Petra
Department of Radiation Therapy and Internal Oncology, Tumor Clinic, Sisters of Charity Hospital, Vinogradska 29, 10000, Zagreb, Croatia.
World J Surg Oncol. 2015 Mar 27;13:127. doi: 10.1186/s12957-015-0535-4.
Dermatomyositis (DM) is characterized by pathognomic cutaneous manifestations (heliotrope rash, periorbital edema, Gottron's papules) and proximal muscle weakness. In this paper, I will present the case of a 48-year-old female patient whose dermatomyositis was initially diagnosed as vasculitis. Following the patient's inadequate response to corticosteroid treatment, clinical and radiologic examinations were performed, showing inoperable gallbladder adenocarcinoma. Although initial chemotherapy led to regression, the dermatomyositis developed an independent course with new pathological changes leading to the progression of the disease. I will also present an overview of case reports in English published so far. Gallbladder carcinoma should be added to the list of malignancies with dermatomyositis and has to be excluded by relevant investigation in women.
皮肌炎（DM）的特征是具有特异性皮肤表现（向阳疹、眶周水肿、Gottron丘疹）和近端肌无力。在本文中，我将介绍一名48岁女性患者的病例，其皮肌炎最初被诊断为血管炎。在患者对皮质类固醇治疗反应不佳后，进行了临床和影像学检查，结果显示为无法手术切除的胆囊腺癌。尽管初始化疗使病情有所缓解，但皮肌炎呈现出独立的病程，并出现了导致疾病进展的新病理变化。我还将概述迄今为止以英文发表的病例报告。胆囊癌应被列入与皮肌炎相关的恶性肿瘤名单中，对于女性患者必须通过相关检查加以排除。
