经导管闭合膜周部室间隔缺损相关并发症。
Complications associated with transcatheter closure of perimembranous ventricular septal defects.
作者信息
Zhou Tao, Shen Xiang-Qian, Zhou Sheng-Hua, Fang Zhen-Fei, Hu Xin-Qun, Zhao Yan-Shu, Qi Shu-Shan, Li Jiang, Lv Xiao-Lin
机构信息
Department of Cardiology, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, China.
出版信息
Catheter Cardiovasc Interv. 2008 Mar 1;71(4):559-63. doi: 10.1002/ccd.21412.
OBJECTIVES
To identify the complications associated with transcatheter closure of perimembranous ventricular septal defects (PmVSD) using the Amplazter PmVSD occluder (AGA Medical, USA).
METHODS
Between October 2002 and November 2006, transcatheter closure PmVSD was attempted in 210 patients and performed in 206 patients. Those patients were followed-up for 6-24 months (mean, 10.6 +/- 3.9 months) to identify the complications.
RESULTS
Device implantation was successfully accomplished in 206 of the 210 patients (98%). Serious complications such as high degree atrioventricular block (AV block), infective endocarditis, and device embolization occurred in eight cases (3.8%). Other complications including mild aortic or tricuspid regurgitation, femoral pseudoaneurysm, and femoral arteriovenous fistula occurred in four cases.
CONCLUSIONS
Transcatheter closure of PmVSD can be performed safely and successfully. But further studies should continue to evaluate the potential complications associated with this procedure.
目的
使用美国AGA Medical公司的Amplazter膜周部室间隔缺损（PmVSD）封堵器，确定经导管封堵PmVSD相关的并发症。
方法
2002年10月至2006年11月期间，210例患者尝试经导管封堵PmVSD，其中206例成功进行了封堵。对这些患者进行了6至24个月（平均10.6±3.9个月）的随访，以确定并发症情况。
结果
210例患者中有206例（98%）成功完成了器械植入。8例（3.8%）出现了严重并发症，如高度房室传导阻滞（AV阻滞）、感染性心内膜炎和器械栓塞。其他并发症包括轻度主动脉或三尖瓣反流、股动脉假性动脉瘤和股动静脉瘘，共4例。
结论
经导管封堵PmVSD可以安全、成功地进行。但仍需进一步研究以持续评估该手术相关的潜在并发症。
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