碳水化合物衍生的烯丙醇、醚和酯的立体定向脱苄环醚化反应以形成乙烯基C-呋喃糖苷。
Stereospecific debenzylative cycloetherification of carbohydrate-derived allylic alcohols, ethers and esters to form vinyl C-furanosides.
作者信息
Cribiù Riccardo, Cumpstey Ian
机构信息
Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden.
出版信息
Chem Commun (Camb). 2008 Mar 14(10):1246-8. doi: 10.1039/b718060h. Epub 2008 Feb 7.
DOI:10.1039/b718060h
PMID:18309432
Abstract
Benzyl ether protected polyhydroxylated alkene compounds containing allylic alcohol, ether or ester functionality undergo a stereospecific cyclisation reaction upon treatment with TFA-acetonitrile-toluene with inversion of configuration at the allylic position and loss of a benzyl ether to give tetrahydrofurans.
摘要
含有烯丙醇、醚或酯官能团的苄基醚保护的多羟基化烯烃化合物，在用三氟乙酸-乙腈-甲苯处理时会发生立体专一性环化反应，在烯丙基位置构型翻转并失去一个苄基醚，生成四氢呋喃。
Zotero 插件