威尔逊病中预防性锌治疗的失败

Failure of prophylactic zinc in Wilson disease.

作者信息

Mishra Devendra, Kalra Veena, Seth Rachna

机构信息

Child Neurology Division, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi 110 029, India.

出版信息

Indian Pediatr. 2008 Feb;45(2):151-3.

PMID:18310797

Abstract

Early institution of prophylactic therapy of asymptomatic Wilson disease patients can prevent the expression of the disease. Zinc is currently preferred therapy for presymptomatic patients. We report onset of symptomatic disease in a presymptomatic patient and deterioration of biochemical parameters in another, despite appropriate zinc therapy.

摘要

对无症状威尔逊病患者尽早进行预防性治疗可预防疾病的发作。锌目前是症状前患者的首选治疗方法。我们报告了一名症状前患者出现症状性疾病，以及另一名患者尽管接受了适当的锌治疗，但生化指标仍恶化。