Percutaneous closure of perivalvular mitral regurgitation with an Amplatzer occluder device in a patient with both prosthetic mitral and aortic valves.

Percutaneous mitral valve closure is a novel technique in evolution as an alternative therapy for nonsurgical candidates with significant mitral regurgitation. Current use has been limited to patients with single prosthetic valves and discrete perivalvular defects. We describe a case of successful percutaneous repair of a mitral perivalvular leak with an Amplatzer ductal occluder in a patient with both prosthetic mitral and aortic valves. In this case, a left ventricle apical approach for access was utilized.