GnRH analogue-induced uterine shrinkage enabling a vaginal hysterectomy and repair in large leiomyomatous uteri.

Gonadotropin-releasing hormone (GnRH) analogue was used to reduce large leiomyomas in three young women who were scheduled to have an abdominal hysterectomy and vaginal plastic repair. Significant size decrease due to the hormonal treatment enabled safe vaginal hysterectomy and repair.